ncRNA name | mmu-miR-495 |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | siRNA transfection, qRT-PCR, Western blot, luciferase reporter assay, immunohistochemistry |
Expression pattern | down-regulated |
Functional description | Overexpression of miR-20a, -20b, -17, -106a, -106b and -495 caused a significant downregulation of HIF1α and VEGF protein levels in ARPE cells exposed to HG+SIR. |
PubMed ID | 24018047 |
Year | 2013 |
Title | MicroRNA-dependent cross-talk between VEGF and HIF1α in the diabetic retina. |
Drug-related ncRNA | NO |
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